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Image Search Results
Journal: mBio
Article Title: Manipulation of regulators of morphogenesis is not sufficient to render a Candida albicans colonizer strain pathogenic
doi: 10.1128/mbio.00415-26
Figure Lengend Snippet: The Ras1-cAMP pathway promotes filamentation in intrinsically low-damage-inducing strains. ( A ) C. albicans strain 101 wild type and 101_ BRG1 FL / BRG1 FL were plated on Spider agar for 7 days at 35°C. ( B ) Colony morphology of clones that were isolated from spontaneously outgrown filaments ( A ) when grown on YEPD or Spider agar, as indicated. ( C and D ) ECE1 expression levels ( C ) and LDH release ( D ) by the clones after exposure to TR146 keratinocytes for 24 h at 37°C, 5% CO 2 . Each symbol represents one sample. The mean ± SD is indicated. Statistical significance was determined using one-way ANOVA comparing each mutant with the corresponding parental strain. * P < 0.05, ** P < 0.01; ns, non-significant ( P > 0.05) ( E ) Mutations in RAS1 identified in the clones shown in panel B .
Article Snippet: Filamentation was assessed on
Techniques: Clone Assay, Isolation, Expressing, Mutagenesis